Editing Exotic Animal Formulary

REFERENCES

1. Abd El-Aty AM, Goudah A, Abo El-Sooud K. Pharmacokinetics, intramuscular bioavailability
and tissue residue profiles of ceftazidime in a rabbit model. Dtsch Tierarztl Wochenschr
2001;108:168-171.
2. Abd El-Aty AM, Goudah A, Abo El-Sooud K, et al. Pharmacokinetics and bioavailability of
florfenicol following intravenous, intramuscular, and oral administration in rabbits. Vet Res
Commun 2004;28:515-524.
3. Abd El-Aty AM, Goudah A, Ismail M, et al. Disposition kinetics of difloxacin in rabbits after
intravenous and intramuscular injection of Dicural. Vet Res Commun 2005;29:297-304.

4. Abo-El-Sooud K, Goudah A. Influence of Pasteurella multocida infection on the pharmacoki-
netic behavior of marbofloxacin after intravenous and intramuscular administrations in rab-
bits. J Vet Pharmacol Ther 2009;33:63-68.

5. Akpek EK, Vittitow J, Verhoeven RS, et al. Ocular surface distribution and pharmacokinet-
ics of a novel ophthalmic 1% azithromycin formulation. J Ocul Pharmacol Ther 2009;

25:433-440.
6. Allen DG, Pringle JK, Smith DA. Handbook of Veterinary Drugs. Philadelphia: JB Lippincott
Co; 1993.

7. Allweiler S, Leach MC, Flecknell PA. The use of propofol and sevoflurane for surgical anaes-
thesia in New Zealand white rabbits. Lab Anim 2010;44:113-117.

8. Audeval-Gerard C, Nivet C, el Amrani A, et al. Pharmacokinetics of ketoprofen in rabbits after
single topical application. Eur J Drug Metab Pharmacokinet 2000;25:227-230.
9. Avunduk AM, Beuerman RW, Warnel ED, et al. Comparison of efficacy of topical and oral
fluconazole treatment in experimental Aspergillus keratitis. Curr Eye Res 2003;26:113-117.
10. Barequet IS, Denton P, Osterhout GJ, et al. Treatment of experimental bacterial keratitis with
topical trovafloxacin. Arch Ophthalmol 2004;122:65-69.
11. Benedetti M, Coupez R, Whomsley R, et al. Comparative pharmacokinetics and metabolism
of levetiracetam, a new anti-epileptic agent, in mouse, rat, rabbit, and dog. Xenobiotic
2004;34:281-300.
12. Bennett RA. Rabbit and rodent orthopedics. Proc North Am Vet Conf 1998:773-774.
13. Bennett RA. Soft tissue surgery in rabbits. Proc North Am Vet Conf 1998:775-776.
14. Bennett RA. Treatment of abscesses in the head of rabbits. Proc North Am Vet Conf 1999:
821-823.
15. Birke L, Molina P, Baker D, et al. Comparison of selamectin and imidacloprid plus permethrin
in eliminating Leporacarus gibbus infestation in laboratory rabbits. J Am Assoc Lab Anim Sci
2009;48:757-762.
16. Blair MJ, Render JA, Morreale R, et al. Granulocyte macrophage colony stimulating factor:
effect on corneal wound healing. Vet Comp Ophthalmol 1997;7:168-172.
17. Bowman DD, Fogelson ML, Carbone LG. Effect of ivermectin on the control of ear mites
(Psoroptes cuniculi) in naturally infested rabbits. Am J Vet Res 1992;53:105-109.
18. Broome RL, Brooks DL. Efficacy of enrofloxacin in the treatment of respiratory pasteurellosis
in rabbits. Lab Anim Sci 1991;41:572-576.
19. Broome RL, Brooks DL, Babish JG, et al. Pharmacokinetic properties of enrofloxacin in rabbits.
Am J Vet Res 1991;52:1835-1841.
20. Brown SA. Intermittent soft stools in rabbits. Proc North Am Vet Conf 1996:849-850.
21. Brown SA. Rabbit urinary tract disease. Proc North Am Vet Conf 1997:785-787.
22. Burgmann P, Percey DH. Antimicrobial drug use in rodents and rabbits. In: Prescott JF,
Baggot JD, eds. Antimicrobial Therapy in Veterinary Medicine. Ames: Iowa State University
Press; 1993:524-541.
23. Cabanes A, Arboix M, Anton JMG, et al. Pharmacokinetics of enrofloxacin after intravenous
and intramuscular injection in rabbits. Am J Vet Res 1992;53:2090-2093.

24. Cam Y, Atasever A, Eraslan G, et al. Experimental infection in rabbits and the effect of treat-
ment with toltrazuril and ivermectin. Exper Parasitol 2008;119:164-172.

25. Cantwell S. Ferret, rabbit, and rodent anesthesia. Vet Clin North Am Exotic Anim Pract
2001;4:169-191.
26. Carceles CM, Fernandez-Varon E, Marin P, et al. Tissue disposition of azithromycin after
intravenous and intramuscular administration to rabbits. Vet J 2007;174:154-159.
27. Carman RJ. Antibiotic-associated diarrhea of rabbits. J Small Exotic Anim Med 1993;2:69-71.
28. Carpenter JW, MG Hawkins. Personal communication. 2011.

29. Carpenter JW, Dryden M, KuKanich B. Efficacy and pharmacokinetics of topical administra-
tion of selamectin in flea-infested rabbits. Am J Vet Res 2012. In press.

30. Carpenter JW, Mashima TY, Gentz EJ, et al. Caring for rabbits: an overview and formulary. Vet
Med 1995;April:340-364.
31. Carpenter JW, Pollock CG, Koch DE, et al. Single- and multiple-dose pharmacokinetics of
marbofloxacin after oral administration to rabbits. Am J Vet Res 2009;70:522-526.
32. Carpenter JW, Pollock CG, Koch DE, et al. Single- and multiple-dose pharmacokinetics of
meloxicam after oral administration to the rabbit (Oryctolagus cuniculus). J Zoo Wildl Med
2009;40:601-606.
33. Cocksholt ID, Douglas EJ, Plummer GF, et al. The pharmacokinetics of propofol in laboratory
animals. Xenobiotica 1992;22:369-375.
34. Collins BR. Antimicrobial drug use in rabbits, rodents, and other small mammals. In:
Antimicrobial Therapy in Caged Birds and Exotic Pets. Trenton: Veterinary Learning Systems
Co; 1995:3-10.

35. Cooper CS, Metcalf-Pate KA, Barat CE, et al. Comparison of side effects between buprenor-
phine and meloxicam used postoperatively in Dutch belted rabbits (Oryctolagus cuniculus).

J Am Assoc Lab Anim Sci 2009;48:279-285.
36. Cooper S, McLellan G, Rycroft A. Conjunctival flora observed in 70 healthy domestic rabbits
(Oryctolagus cuniculus). Vet Rec 2001;149:232-235.
37. Deren YT, Ozdek S, Kalkanci A, et al. Comparison of antifungal efficacies of moxifloxacin,
liposomal amphotericin B, and combination treatment in experimental Candida albicans
endophthalmitis in rabbits. Can J Microbiol 2010;56:1-7.
38. Doerning BJ, Brammer DW, Chrisp CE, et al. Nephrotoxicity of tiletamine in New Zealand
white rabbits. Lab Anim Sci 1992;42:267-269.
39. Drago F, Emmi I, Marino V. Effects of beta-blockers association with pilocarpine on rabbit
intraocular pressure and heart rate. Pharm Res 1997;35:299-302.

40. Drummond JC. MAC for halothane, enflurane, and isoflurane in the New Zealand white rab-
bit: and a test for the validity of MAC determinations. Anesthesiology 1985;62:336-338.

41. Dundaroz R, DeGim T, Sizlan A, et al. Intracavernous application of diazepam: an alternative
route of the seizure treatment—an experimental study in rabbits. Pediatr Int 2002;44:163-167.
42. Egger CM, Souza MJ, Greenacre CB, et al. Effect of intravenous administration of tramadol
hydrochloride on the minimum alveolar concentration of isoflurane in rabbits. Am J Vet Res
2009;70:945-949.
43. Eisle PH. Anesthesia for the rabbit. Proc North Am Vet Conf 1997:792-794.
44. Elmas M, Uney K, Yazar E, et al. Pharmacokinetics of enrofloxacin following intravenous and
intramuscular administration in Angora rabbits. Res Vet Sci 2007;82:242-245.
45. Fairham J, Harcourt-Brown F. Preliminary investigation of the vitamin D status of pet rabbits.
Vet Rec 1999;145:452-454.
46. Farmaki R, Koutinas AF, Papazahariadou MG, et al. Effectiveness of a selamectin spot-on
formulation in rabbits with sarcoptic mange. Vet Rec 2009;164:431-432.

47. Fernandez-Varon E, Bovaira MJ, Espuny A, et al. Pharmacokinetic-pharmacodynamic integra-
tion of moxifloxacin in rabbits after intravenous, intramuscular and oral administration. J Vet

Pharmacol Ther 2005;28:343-348.
48. Fiorello CV. Personal observation. 2011.
49. Fish RE, Besch-Williford C. Reproductive disorders in the rabbit and guinea pig. In: Kirk RW,
Bonagura JD, eds. Kirk’s Current Veterinary Therapy XI: Small Animal Practice. Philadelphia:
WB Saunders Co; 1992:1175-1179.
50. Flecknell P. Medetomidine and atipamezole: potential uses in laboratory animals. Lab Anim
1997;26:21-25.
51. Flecknell PA. Laboratory Animal Anesthesia. London: Academic Press, 1987.
52. Flecknell PA. Post-operative analgesia in rabbits and rodents. Lab Anim 1991;20:34-37.
53. Foley P, Henderson A, Bissonette E, et al. Evaluation of fentanyl transdermal patches in rabbits:
blood concentrations and physiologic response. Comp Med 2001;51:239-244.

54. Fontes-Sousa AP, Brás-Silva C, Moura C, et al. M-mode and Doppler echocardiographic refer-
ence values for male New Zealand white rabbits. Am J Vet Res 2006;67:1725-1729.

55. Gallina G, Lucatello L, Drigo I, et al. Kinetics and intrapulmonary disposition of tilmicosin
after single and repeated oral bolus administrations to rabbits. Vet Res Commun 2010;34:
S69-S72.
56. Gillett CS. Selected drug dosages and clinical reference data. In: Manning PJ, Ringler DH,
Newcomer CE, eds. The Biology of the Laboratory Rabbit. 2nd ed. San Diego: Academic Press;
1994:467-472.

57. Gokbulut C, Biligili A, Kart A, et al. Plasma dispositions of ivermectin, doramectin and mox-
idectin following subcutaneous administration in rabbits. Lab Anim 2010;44:138-142.

58. Green LC, Callegan MC, Engel LS, et al. Pharmacokinetics of topically applied ciprofloxacin in
rabbit tears. Jpn J Ophthalmol 1996;40:123-126.
59. Grint NJ, Murison PJ. A comparison of ketamine-midazolam and ketamine-medetomidine
combinations for induction of anaesthesia in rabbits. Vet Anaesth Analg 2008;35:113-121.
60. Harcourt-Brown F. Textbook of Rabbit Medicine. Oxford: Butterworth-Heinemann; 2002.
61. Harkness JE, Wagner JE. The Biology and Medicine of Rabbits and Rodents. 3rd ed. Philadelphia:
Lea and Febiger; 1989.
62. Harkness JE, Wagner JE. The Biology and Medicine of Rabbits and Rodents. 4th ed. Philadelphia:
Williams & Wilkins; 1995.
63. Harrenstien L. Critical care of ferrets, rabbits, and rodents. Semin Avian Exotic Pet Med
1994;3:217-228.
64. Harvey C. Rabbit and rodent skin diseases. Semin Avian Exotic Pet Med 1995;4:195-204.
65. Hawkins MG, Vernau W, Drazenovich TL, et al. Results of cytologic and microbiologic
analysis of bronchoalveolar lavage fluid in New Zealand white rabbits. Am J Vet Res 2008;69:
572-578.
66. Heard DJ. Principles and techniques of anesthesia and analgesia for exotic practice. Vet Clin
North Am Small Anim Pract 1993;23:1301-1327.
67. Heard DJ. Anesthesia, analgesia, and sedation of small mammals. In: Quesenberry KE,
Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery. 2nd ed.
St Louis: WB Saunders Co; 2004:356-369.

68. Hellebrekers LJ, de Boer EJW, van Zuylen MA, et al. A comparison between medetomidine-
ketamine and medetomidine-propofol anaesthesia in rabbits. Lab Anim 1997;31:58-69.

69. Henke J, Astner S, Brill T, et al. Comparative study of three intramuscular anaesthetic

combinations (medetomidine-ketamine, medetomidine-fentanyl-midazolam and xylazine-
ketamine) in rabbits. Vet Anaesth Analg 2005;32:261-270.

70. Hersey-Benner C. Diarrhea in a rabbit. Lab Anim 2008;37:347-349.
71. Hillyer EV. Pet rabbits. Vet Clin North Am Small Anim Pract 1994;24:25-64.
72. Hiraoka T, Kaji Y, Wakabayashi T, et al. Comparison of micafungin and fluconazole for
experimental Candida keratitis in rabbits. Cornea 2007;26:336-342.
73. Hu L, Liu C, Shang C, et al. Pharmacokinetics and improved bioavailability of toltrazuril after
oral administration to rabbits. J Vet Pharmacol Ther 2010;33:503-506.
74. Huerkamp MJ. Anesthesia and postoperative management of rabbits and pocket pets. In:
Bonagura JD, ed. Kirk’s Current Veterinary Therapy XII: Small Animal Practice. Philadelphia:
WB Saunders Co; 1995:1322-1327.
75. Huston SM, Quesenberry KE. Cardiovascular and lymphoproliferative diseases In:

Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Sur-
gery. 2nd ed. St Louis: WB Saunders Co; 2004:211-220.

76. Hutchinson MJ, Jacobs DE, Bell GD, et al. Evaluation of imidacloprid for the treatment and
prevention of cat flea (Ctenocephalides felis felis) infestations on rabbits. Vet Rec 2001;148:
695-696.
77. Idid S, Lee C. Effects of Fuller’s Earth and activated charcoal on oral absorption of paraquat
in rabbits. Clin Exp Pharmacol Physiol 1996;23:679-681.
78. Ivey E. Personal communication. 2002.
79. Ivey ES, Morrisey JK. Therapeutics for rabbits. Vet Clin North Am Exotic Anim Pract
2000;3:183-220.
80. Jass A, Matiasek K, Henke J, et al. Analysis of cerebrospinal fluid in healthy rabbits and rabbits
with clinically suspected encephalitozoonosis. Vet Rec 2008;162:618-622.
81. Jenkins J. Rabbits. In: Jenkins JR, Brown SA, eds. A Practitioner’s Guide to Rabbits and Ferrets.
Lakewood, CO: American Animal Hospital Association; 1993:1-42.
82. Jenkins J. Rabbit Drug Doses. Lakewood, CO: American Animal Hospital Association; 1995.
83. Jepson L. Exotic Animal Medicine: A Quick Reference Guide. Philadelphia: Saunders/Elsevier;
2009.
84. Kanbur M, Atalay O, Ica A, et al. The curative and antioxidative efficiency of doramectin and
doramectin1vitamin AD3E treatment on Psoroptes cuniculi infestation in rabbits. Res Vet Sci
2008;85:291-293.
85. Kaya D, Inceboz T, Kolatan E, et al. Comparison of efficacy of ivermectin and doramectin
against mange mite (Sarcoptes scabiei) in naturally infested rabbits in Turkey. Vet Ital
2010;46:51-56.
86. Kern TJ. Rabbit and rodent ophthalmology. Semin Avian Exotic Pet Med 1997;6:138-145.
87. Kiel JW, Patel P. Effects of timolol and betaxolol on choroidal blood flow in the rabbit. Exp
Eye Res 1998;67:501-507.
88. Kim MS, Lim JH, Hwang YH, et al. Plasma disposition of toltrazuril and its metabolites,
toltrazuril sulfoxide and toltrazuril sulfone, in rabbits after oral administration. Vet Parasitol
2010;169:51-56.
89. Kim SH, Lee JY, Jun HK, et al. Efficacy of selamectin in the treatment of cheyletiellosis in pet
rabbits. Vet Dermatol 2008;19:26-27.
90. Kirkpatrick WR, Vallor AC, McAtee RK, et al. Combination therapy with terbinafine and
amphotericin B in a rabbit model of experimental invasive aspergillosis. Antimicrob Agents
Chemother 2005;49:4751-4753.
91. Kirschner SE. Ophthalmologic diseases in small mammals. In: Hillyer EV, Quesenberry KE,
eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery. Philadelphia: WB Saunders
Co; 1997:339-345.
92. Koc F, Ozturk M, Kadioglu Y, et al. Pharmacokinetics of florfenicol after intravenous
and intramuscular administration in New Zealand white rabbits. Res Vet Sci 2009;87:
102-105.
93. Korting HC, Walther D, Riethmüller U, et al. Ceftriaxone given repeatedly cures manifest
syphilis in the rabbit. Chemother 1987;33:376-380.
94. Kosravi E, Elena P, Hariton C. Allergic conjunctivitis and uveitis models: reappraisal with
some marketed drugs. Inflamm Res 1995;44:47-54.

95. Kozer E, Levicheck Z, Hoshino N, et al. The effect of amitriptyline, gabapentin, and carbam-
azepine on morphine-induced hypercarbia in rabbits. Anesth Analg 2008;107:1216-1222.

96. Kraus AL, Wesbroth SH, Flatt RE, et al. Biology and diseases of rabbits. In: Fox JG, Cohen BJ,
Loew FM, eds. Laboratory Animal Medicine. Orlando: Academic Press; 2000:207-240.
97. Krempels D, Cotter M, Stanzione G. Ileus in domestic rabbits. Exotic DVM 2000;2:19-21.
98. Kurtdede A, Karaer Z, Acar A, et al. Use of selamectin for the treatment of psoroptic and
sarcoptic mite infestation in rabbits. Vet Dermatol 2007;18:18-22.
99. Lee M, Kallal S, Feldman M. Omeprazole prevents indomethacin-induced gastric ulcers in
rabbits. Aliment Pharmacol Ther 1996;10:571-576.
100. Lipman NS, Marini RP, Erdman SE. A comparison of ketamine/xylazine and ketamine/
xylazine/acepromazine anesthesia in the rabbit. Lab Anim Sci 1990;40:395-398.
101. Lipman NS, Marini RP, Flecknell PA. Anesthesia and analgesia in rabbits. In: Kohn DF,
Wixson SK, White WJ, et al, eds. Anesthesia and Analgesia in Laboratory Animals. New York:
Academic Press; 1997:205-232.
102. Longley L. Anaesthesia of Exotic Pets. Philadelphia: Saunders/Elsevier; 2008.

103. Louie A, Liu QF, Drusano GL, et al. Pharmacokinetic studies of fluconazole in rabbits char-
acterizing doses which achieve peak levels in serum and area under the concentration-time

curve values which mimic those of high-dose fluconazole in humans. Antimicrob Agents
Chemother 1998;42:1512-1514.
104. Lukehart SA, Fohn MJ, Baker-Zander SA. Efficacy of azithromycin for therapy of active
syphilis in the rabbit model. J Antimicrob Chemother 1990;25:91-99.
105. Maciejewska-Paszek I, Pawlowska-Góral K, Kostrzewski M, et al. The influence of small
doses of paracetamol on rabbit liver. Exp Toxicol Pathol 2007;59:139-141.
106. Marangos MN, Zhu Z, Nicolau DP, et al. Disposition of ofloxacin in female New Zealand
white rabbits. J Vet Pharmacol Ther 1997;20:17-20.
107. Marini RP, Avison DL, Corning BF, et al. Ketamine-xylazine-butorphanol: a new anesthetic
combination for rabbits. Lab Anim Sci 1992;42:57-62.
108. McElroy DE, Ravis WR, Clark CH. Pharmacokinetics of oxytetracycline hydrochloride in
rabbits. Am J Vet Res 1987;48:1261-1263.
109. McGee DH, Holt WF, Kastner PR, et al. Safety of moxifloxacin as shown in animal and in
vitro studies. Surv Ophthalmol 2005;50(Suppl 1):S46-54.
110. McKay SG, Morck DW, Merrill JK, et al. Use of tilmicosin for treatment of pasteurellosis
in rabbits. Am J Vet Res 1996;57:1180-1184.
111. McNitt JI, Cheeke PR. Rabbit Production. Danville, IL: Interstate Printers & Publishers; 1996.

112. McTier TL, Hair JA, Walstrom DJ, et al. Efficacy and safety of topical administration of sela-
mectin for treatment of ear mite infestation in rabbits. J Am Vet Med Assoc 2003;223:322-324.

113. Mencke N, Bach T. Managing gastrointestinal helminths in small mammals. Comp Cont Educ
Pract 2007;29:13-16.
114. Mercier P, Morel-Saives A, Verdelhan S, et al. Tolerance of decoquinate in the rabbit. Proc 8th
World Rabbit Congr 2004;597-600.

115. Miller JL, Schell WA, Wills EA, et al. In vitro and in vivo efficacies of the new triazole alba-
conazole against Cryptococcus neoformans. Antimicrob Agents Chemother 2004;48:384-387.

116. Millis DL, Walshaw R. Elective castrations and ovariohysterectomies in pet rabbits. J Am
Anim Hosp Assoc 1992;28:491-498.
117. More RC, Kody MH, Kabo JM, et al. The effects of two nonsteroidal antiinflammatory drugs
on limb swelling, joint stiffness, and bone torsional strength following fracture in a rabbit
model. Clin Orthop Relat Res 1989; Oct:306-311.
118. Morrisey JK. Ectoparasites of small mammals. Proc North Am Vet Conf 1998;844-845.
119. Morrisey JK. Personal communication. 2004.
120. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets,
Rabbits, and Rodents: Clinical Medicine and Surgery. 3rd ed. St Louis: Saunders/Elsevier;
2012:566-575.
121. Mullan S, Main D. Behaviour and personality of pet rabbits and their interactions with their
owners. Vet Rec 2007;160:516-520.
122. Murphy KL, Roughan JV, Baxter MG, et al. Anaesthesia with a combination of ketamine and
medetomidine in the rabbit: effect of premedication with buprenorphine. Vet Anaesth Analg
2010;37:222-229.
123. Nelson CL, McLaren SG, Skinner RA, et al. The treatment of experimental osteomyelitis by
surgical debridement and the implantation of calcium sulfate tobramycin pellets. J Orthop
Res 2002;20:643-647.
124. Ng EW, Joo MJ, Au Eong KG, et al. Ocular toxicity of intravitreal trovafloxacin in the
pigmented rabbit. Curr Eye Res 2003;27:387-393.
125. Nicolau DP, Freeman CD, Nightingale CH, et al. Pharmacokinetics of minocycline and
vancomycin in rabbits. Lab Anim Sci 1993;43:222-225.
126. Nielson VG, Sidhartha T, Brix AE, et al. Hextend® (hetastarch solution) decreases multiple

organ injury and xanthine oxidase release after hepatoenteric ischemia-reperfusion in rab-
bits. Crit Care Med 1997;25:1565-1574.

127. Norcross EW, Sanders ME, Moore Q, et al. Comparative efficacy of besifloxacin and other
fluoroquinolones in a prophylaxis model of penicillin-resistant Streptococcus pneumoniae
rabbit endophthalmitis. J Ocul Pharmacol Ther 2010;26:237-243.

128. Ofoefule SI, Onuoha LC, Okonta MJ, et al. Effect of activated charcoal on isoniazid absorp-
tion in rabbits. Boll Chim Farm 2001;140:183-186.

129. Okerman L. Diseases of Domestic Rabbits. 2nd ed. Oxford: Blackwell Scientific Publications;
1994.
130. Okerman L, Devriese LA, Gevaert D, et al. In vivo activity of orally administered antibiotics
and chemotherapeutics against acute septicaemic pasteurellosis in rabbits. Lab Anim
1990;24:341-344.

131. Ollivier F, Delverdier M, Regnier A. Tolerance of the rabbit cornea to an n-butyl-ester cyano-
acrylate adhesive (Vetbond®). Vet Ophthalmol 2001;4:261-266.

132. Orr HE, Roughan JV, Flecknell PA. Assessment of ketamine and medetomidine anaesthesia
in the domestic rabbit. Vet Anaesth Analg 2005;32:271-279.
133. Ostergaard C, Sorensen TK, Knudsen JD, et al. Evaluation of moxifloxacin, a new

8-methoxyquinolone, for treatment of meningitis caused by a penicillin-resistant pneumo-
coccus in rabbits. Antimicrob Agents Chemother 1998;42:1706-1712.

134. Ozturk F, Kurt E, Inan UU, et al. The effects of prolonged acute use and inflammation on the
ocular penetration of topical ciprofloxacin. Int J Pharm 2000;204:97-100.
135. Pan B, Wang M, Xu F, et al. Efficacy of an injectable formulation of eprinomectin against
Psoroptes cuniculi, the ear mange mite in rabbits. Vet Parasitol 2006;137:386-390.
136. Pan BL, Zhang YF, Suo X, et al. Effect of subcutaneously administered diclazuril on the
output of Eimeria species oocysts by experimentally infected rabbits. Vet Rec 2008;162:
153-155.
137. Patterson TF, Fothergill AW, Rinaldi MG. Efficacy of itraconazole solution in a rabbit model
of invasive aspergillosis. Antimicrob Agents Chemother 1993;37:2307-2310.
138. Paul-Murphy J, Ramer JC. Urgent care of the pet rabbit. Vet Clin North Am Exotic Anim Pract
1998;1:127-152.
139. Percy DH, Black WD. Pharmacokinetics of tetracycline in the domestic rabbit following
intravenous or oral administration. Can J Vet Res 1988;52:5-11.
140. Petraitis V, Petraitiene R, Groll AH, et al. Comparative antifungal activities and plasma
pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive
pulmonary aspergillosis in persistently neutropenic rabbits. Antimicrob Agents Chemother
2002;46:1857-1869.
141. Pichardo C, Docobo-Pérez F, Pachón-Ibáñez ME, et al. Efficacy of beta-lactams against
experimental pneumococcal endocarditis caused by strains with different susceptibilities to
penicillin. J Antimicrob Chemother 2005;56:732-737.
142. Plumb D. Plumb’s Veterinary Drug Handbook. 5th ed. Ames: Blackwell Publishing; 2005.

143. Proksch JW, Ward KW. Ocular pharmacokinetics/pharmacodynamics of besifloxacin, moxi-
floxacin, and gatifloxacin following topical administration to pigmented rabbits. J Ocul

Pharmacol Ther 2010;26:449-458.
144. Quesenberry KE. Rabbits. In: Birchard SJ, Sherding RG, eds. Saunders Manual of Small
Animal Practice. Philadelphia: WB Saunders Co; 1994:1345-1362.
145. Quesenberry KE. Personal communication. 2002.

146. Quimby JM, Gustafson DL, Samber BJ, et al. Studies on the pharmacokinetics and pharma-
codynamics of mirtazapine in healthy young cats. J Vet Pharmacol Ther 2010;epub.

147. Ramer JC, Paul-Murphy J, Benson KG. Evaluating and stabilizing critically ill rabbits—
Part I. Comp Cont Educ Pract 1999;21:30-33.
148. Ramer JC, Paul-Murphy J, Benson KG. Evaluating and stabilizing critically ill rabbits—
Part II. Comp Cont Educ Pract 1999;21:36-40.
149. Redrobe S, Gakos G, Elliot SC, et al. Comparison of toltrazuril and sulphadimethoxine in the
treatment of intestinal coccidiosis in pet rabbits. Vet Rec 2010;167:287-290.

150. Reusch B, Murray J, Papsouliotis K, et al. Urinary protein:creatinine ratio in rabbits in rela-
tion to their serological status to Encephalitozoon cuniculi. Vet Rec 2009;164:293-295.

151. Rosenthal K. Epidural anesthesia. Proc North Am Vet Conf 1996:876.

152. Rougier S, Galland D, Boucher S, et al. Epidemiology and susceptibility of pathogenic bacte-
ria responsible for upper respiratory tract infections in pet rabbits. Vet Microbiol 2006;115:

192-198.
153. Saito K, Hasegawa A. Chloramphenicol treatment for rabbit syphilis. J Vet Med Sci
2004;66:1301-1304.
154. Samudre S, Lattanzio F, Lossen V, et al. Lacritin, a novel human tear glycoprotein, promotes
sustained basal tearing and is well-tolerated. Invest Ophthalmol Vis Sci 2010;epub 10.1167/
ivos.10-6220.
155. Sanati H, Ramos C, Bayer A, et al. Combination therapy with amphotericin B and fluconazole
against invasive candidiasis in neutropenic-mouse and infective-endocarditis rabbit models.
Antimicrob Agents Chemother 1997;41:1345-1348.
156. Scheller MS, Daidman LJ, Partridge BL. MAC of sevoflurane in humans and the New Zealand
white rabbit. Can J Anesth 1988;35:153-156.
157. Schuchman SM. Individual care and treatment of rabbits, mice, guinea pigs, hamsters, and
gerbils. In: Kirk RW, ed. Current Veterinary Therapy X: Small Animal Practice. Philadelphia:
WB Saunders Co; 1989:738-765.
158. Sharpnack DD, Mastin JP, Childress CP, et al. Quinolone arthropathy in juvenile New Zealand
white rabbits. Lab Anim Sci 1994;44:436-442.
159. Shirtliff M, Mader J, Calhoun J. Oral rifampin plus azithromycin or clarithromycin to treat
osteomyelitis in rabbits. Clin Orthop 1999;359:229-236.
160. Smith DA, Burgmann PM. Formulary. In: Hillyer EV, Quesenberry KE, eds. Ferrets, Rabbits,
and Rodents: Clinical Medicine and Surgery. Philadelphia: WB Saunders Co; 1997:392-403.

161. Sorensen KN, Sobel RA, Clemons KV, et al. Comparative efficacies of terbinafine and fluco-
nazole in treatment of experimental coccidioidal meningitis in a rabbit model. Antimicrob

Agents Chemother 2000;44:3087-3091.
162. Souza MJ, Greenacre CB, Cox SK. Pharmacokinetics of orally administered tramadol in
domestic rabbits (Oryctolagus cuniculus). Am J Vet Res 2008;69:979-982.
163. Steinleitner A, Lambert H, Kazensky C, et al. Reduction of primary postoperative adhesion
formation under calcium channel blockade in the rabbit. J Surg Res 1990;48:42-45.

164. Stiles J, Didier E, Ritchie B, et al. Encephalitozoon cuniculi in the lens of a rabbit with phaco-
clastic uveitis: confirmation and treatment. Vet Comp Ophthalmol 1997;7:233-238.

165. Suter C, Muller-Doblies UU, Hatt JM, et al. Prevention and treatment of Encephalitozoon
cuniculi infection in rabbits with fenbendazole. Vet Rec 2001;148:478-480.
166. Swartout MS, Gerken DF. Lead-induced toxicosis in two domestic rabbits. J Am Vet Med
Assoc 1987;191:717-719.
167. Taylor KH. Orphan rabbits. In: Gage LJ, ed. Hand-rearing Wild and Domestic Mammals.
Ames: Iowa State Press; 2002:5-12.
168. Thomas P, Samant D, Zhu Z, et al. Long-term topical cyclosporine treatment improves tear

production and reduces keratoconjunctivitis in rabbits with induced autoimmune dacryoad-
enitis. J Ocul Pharmacol Ther 2009;25:285-291.

169. Toshida H, Nakayasu K, Kanai A. Effect of cyclosporine A eyedrops on tear secretion in the
rabbit. Jpn J Ophthalmol 1998;42:168-173.
170. Turner P, Chen H, Taylor W. Pharmacokinetics of meloxicam in rabbits after single and
repeat oral dosing. Comp Med 2006;56:63-67.
171. Uebelhart D, Thonar EJ, Zhang JW, et al. Protective effect of exogenous chondroitin 4,
6-sulfate in the acute degradation of articular cartilage in the rabbit. Osteoarthr Cartilage
1998;6(Suppl A):6-13.

172. Ueng SW, Yuan LJ, Lee N, et al. In vivo study of hot compressing molded 50:50 poly
(DL-lactide-co-glycolide) antibiotic beads in rabbits. J Orthop Res 2002;20:654-661.
173. Vanparijs O, Desplenter L, Marsboom R. Efficacy of diclazuril in the control of intestinal
coccidiosis in rabbits. Vet Parasitol 1989;34:185-190.
174. Wagner R, Wendlberger U. Field efficacy of moxidectin in dogs and rabbits naturally infested
with Sarcoptes spp., Demodex spp., and Psoroptes spp. mites. Vet Parasitol 2000;93:149-158.
175. Walsh TJ, Petraitis V, Petraitiene R, et al. Experimental pulmonary aspergillosis due to
Aspergillus terreus: pathogenesis and treatment of an emerging fungal pathogen resistant to
amphotericin B. J Infect Dis 2003;188:305-319.
176. Waterbury L, Flach A. Comparison of ketorolac tromethamine, diclofenac sodium, and
loteprednol etabonate in an animal model of ocular inflammation. J Ocul Pharmacol Ther
2006;22:155-159.
177. Weisbroth SH, Flatt RE, Kraus AL. The Biology of the Laboratory Rabbit. New York: Academic
Press; 1975.

178. Welch WD, Lu YS, Bawdon RE. Pharmacokinetics of penicillin-G in serum and nasal wash-
ings of Pasteurella multocida-free and -infected rabbits. Lab Anim Sci 1987;37:65-68.

179. Wen H, Pan B, Wang F, et al. The effect of self-licking behavior on pharmacokinetics of eprinomectin and clinical efficacy against Psoroptes cuniculi in topically administered rabbits.
Parasitol Res 2010;106:607-613.
180. Wixson SK. Anesthesia and analgesia. In: Manning PJ, Ringler DH, Newcomer CE, eds.
The Biology of the Laboratory Rabbit. 2nd ed. San Diego: Academic Press; 1994.

181. Yu GY, Yan CH, Yu XG, et al. Effects of chelation therapy with succimer in young rabbits of
moderate lead poisoning. Zhonghua Yu Fang Yi Xue Za Zhi 2009;43:8-13.

182. Zhou JY, Xu PF, Chen H, et al. Therapeutic effect of ceftazidime in a rabbit model of peritonitis caused by Escherichia coli producing CTX-M-14 extended-spectrum beta-lactamase.
Zhonghua Jie He He Hu Xi Za Zhi 2005;28:689-693.