Difference between revisions of "Advanced Color Genetics"

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=More Advanced Color Genetics:=
= More Advanced Color Genetics =


== Broken Locus ==
* '''En – Broken''' [[File:Geneiticx3_Brokens.jpg|thumb|Broken]] 


==BROKEN LOCI==
The Broken pattern is dominant over solid. Rabbits homozygous for the Broken gene are called '''Charlies''' and should only be carefully bred. Homozygous Broken carries a ~70% probability of producing rabbits with megacolon, a digestive disorder.


*En-broken [[File:Geneiticx3 Brokens.jpg|thumb|Broken]]
== Vienna ==
* '''V – Vienna''' [[File:Geneiticx3_Vienna.jpg|thumb|Vienna]]


The broken Pattern is dominate to solid. Rabbits with two Broken Geans are called Charlies and should be only very carefully bred becuse the Broken gene when double up carries a 70% probability of producing a Rabbit with megacolon a digestive tract disorder.
Vienna is a co-dominant gene. Two copies (vv) produce '''Blue-Eyed White (BEW)''' rabbits. Rabbits with one copy (Vv) are carriers, sometimes showing random white markings and blue eye coloration in one, part, or both eyes. BEW is only expressed in homozygous recessive rabbits (vv).


==Vienna==
== Wideband ==
*V-Vienna [[File:Geneiticx3 Vienna.jpg|thumb|Vienna]]
* '''W – Wideband'''  


Vienna is most frequently  known for Blue eye white as  to copies of "vm" will produce  a solid white rabbit with blue eyes. Vienna is a co-dominate gene, and a "Vmvm" rabbit is a Vienna carrier, in this case some random white markings can bleed through including the brilliant blue eye color in one , part of or both eyes.
Wideband is a trait modifier affecting Agouti-based rabbits. It extends the band coverage, especially in Chestnut, Red, and Chinchilla rabbits: 


==Wideband==
* Chestnut → larger area of pheomelanin, less white, more red/yellow on the belly 
*W-Wideband
* Chinchilla → more white on the coat and belly 
* Red → solid red belly extending from back 


Wide band  is a trait modifier that will effect Agouti based rabbits. the wide band gene extends the band coverage, primarily on Chestnuts, Reds, and  Chinchillas.  a chestnut will have a larger area of Pheomelanin showing on the coat and less white, and more red/yellow on it's belly(Coppers), a Chinchilla with have more white on it's coat and more white on it's belly, and a red will have a more solid red belly extended from it's back. Wide band high rufus reds and chestnuts  are the most sought after to improve color in a new Zealand red program.
Wideband high-rufus Reds and Chestnuts are desirable in New Zealand Red programs.


==Dutch==
* Normal bandwidth: dominant "W" 
*Du-Dutch
* Wideband: homozygous recessive "ww"


==Silver==
== Dutch ==
*Si-Silver
* '''Du''' – regular color 
* '''dud''' – Dutch dark 
* '''duw''' – Dutch white 


=Modifiers=
[Reference PDF](https://www.adhrc.com/Forms/Color%20Genetics%20of%20the%20Dwarf%20Hotot.pdf)


==Intensity of Red==
== Silver ==
* '''Si – Silver''' 


[[File:Geneiticx3 intensity.jpg|thumb|Intesity]]
The Silver gene produces hairs that are fully white from root to tip, evenly intermixed with body-color hairs.
The intensity of Red  is a gene modifier that controls how saturated the Pheomelanin is in a rabbits coat.  We refer to this as Rufus. A rabbit with very little intensity can look almost like a dirty white, while a Rabbit with extremely high Rufus can present as a deep mahogany maroon color.


==Extent of Broken Pattern==
== Lutino ==
[[File:Lutino.jpg|200px|thumb|left|Lutino Rabbit]] 


[[file:Geneiticx3-29.jpg|thumb|Extent of coverage]]
The Lutino coloration is a '''p mutation''' affecting an integral membrane protein involved in pigmentation. This mutation reduces eumelanin production in both the eyes and coat, creating pink eyes and lighter coat colors. 
*"Charlie "
*Broken
*Blanket
*Booted


==Codominant genes:==
* Recessive: P = normal, p = mutation. Homozygous pp expresses pink eyes and coat color change. 
* Genotypes:
  * Basic orange Lutino: A_B_C_D_eepp 
  * Cream Lutino (“Shadow”): A_B_C_D_E_pp 


*ej-Harliquen
The Lutino gene functions similarly to the non-extension gene but with pink eyes and less effect on pheomelanin. It has been studied extensively in mice (Castle 1909) and rabbits (SoftPawsRabbits, 1985–2014). 
*Chl- Chinchilla Light/Shaded
 
References: 
1. Rosemblat et al., 1994, PNAS 91:12071–12075 
2. Russell, Genetics 34:146, 1949 
3. Castle, Science 30(766):313–314, 1909 
[SoftPawsRabbits Lutino Gene](https://softpawsrabbits.weebly.com/the-lutino-gene.html)
 
== Modifiers ==
Modifiers are not genes themselves but affect the extent of coverage or intensity of rabbit coat colors.
 
=== Intensity of Red ===
[[File:Geneiticx3_intensity.jpg|thumb|Intensity]] 
 
* Intensity of red (“Rufus”) controls pheomelanin saturation. 
* Low intensity → almost dirty white 
* High intensity → deep mahogany/maroon 
* Rufus also affects pigment saturation in other colors (e.g., rich black vs. dull charcoal)
 
=== Extent of Broken Pattern ===
[[File:Geneiticx3-29.jpg|thumb|Extent of Coverage]] 
 
* Charlie 
* Broken 
* Blanket 
* Booted 
 
=== Co-dominant, Cryptic, and Ghost Presentations ===
Some genes present partially dominant traits, show stronger expression when homozygous, or produce “phantom” colors.
 
==== ej – Harlequin ====
[[File:Harliquenized_Opal-01-1.jpeg|200px|thumb|Harlequin Opal]] 
[[File:HarlenquinizedChinchilla.jpg|200px|thumb|Harlequin Chinchilla]] 
 
* Harlequin (ej) can appear in: 
  * Self: aa, Eej 
  * Chinchilla: A, chd, Eej 
  * Chestnut: A, Eej 
* Ej paired with Steel (Es) can produce “phantom black” or super steel: subtle barring visible only in sunlight or on the belly.
 
==== chl – Chinchilla Light / Shaded ====
* chlchl → Seal (intense shaded pattern) 
* chdchl → Intermediate shaded pattern
 
==== Es – Steel ====
* Genotypes: EsEs, Ese, Esej 
* Can present as solid black in some cases 
 
==== Ed – Dominant Black ====
* Extends eumelanin fully on Agouti rabbits (ABCDEd) → appears self black 
* Can produce cryptic self rabbits 
* Testing: breed suspected Ed rabbits with self-colored rabbits or red rabbits to confirm genotype
 
References: 
* [Oregon State Extension: Rabbit Coat Genetics Gallery](https://extension.oregonstate.edu/gallery/rabbit-coat-color-genetics-gallery) 
* [Understanding Genetics Behind Rabbit Coat Colors Part 2](https://extension.oregonstate.edu/animals-livestock/poultry-rabbits/understanding-genetics-behind-rabbit-coat-colors-part-2-coat) 
* [The Nature Trail: Color E Extension Series](https://thenaturetrail.com/rabbit-genetics/color-e-extension-series-steel-tricolor-locus/) 
* [Frontiers in Genetics, 2019](https://www.frontiersin.org/articles/10.3389/fgene.2019.00875/full) 
* [MDPI: Allele ED & ES](https://www.mdpi.com/2076-3417/11/1/373/htm)

Latest revision as of 18:38, 16 August 2025

More Advanced Color Genetics[edit | edit source]

Broken Locus[edit | edit source]

  • En – Broken
    Broken

The Broken pattern is dominant over solid. Rabbits homozygous for the Broken gene are called Charlies and should only be carefully bred. Homozygous Broken carries a ~70% probability of producing rabbits with megacolon, a digestive disorder.

Vienna[edit | edit source]

  • V – Vienna
    Vienna

Vienna is a co-dominant gene. Two copies (vv) produce Blue-Eyed White (BEW) rabbits. Rabbits with one copy (Vv) are carriers, sometimes showing random white markings and blue eye coloration in one, part, or both eyes. BEW is only expressed in homozygous recessive rabbits (vv).

Wideband[edit | edit source]

  • W – Wideband

Wideband is a trait modifier affecting Agouti-based rabbits. It extends the band coverage, especially in Chestnut, Red, and Chinchilla rabbits:

  • Chestnut → larger area of pheomelanin, less white, more red/yellow on the belly
  • Chinchilla → more white on the coat and belly
  • Red → solid red belly extending from back

Wideband high-rufus Reds and Chestnuts are desirable in New Zealand Red programs.

  • Normal bandwidth: dominant "W"
  • Wideband: homozygous recessive "ww"

Dutch[edit | edit source]

  • Du – regular color
  • dud – Dutch dark
  • duw – Dutch white

[Reference PDF](https://www.adhrc.com/Forms/Color%20Genetics%20of%20the%20Dwarf%20Hotot.pdf)

Silver[edit | edit source]

  • Si – Silver

The Silver gene produces hairs that are fully white from root to tip, evenly intermixed with body-color hairs.

Lutino[edit | edit source]

Lutino Rabbit

The Lutino coloration is a p mutation affecting an integral membrane protein involved in pigmentation. This mutation reduces eumelanin production in both the eyes and coat, creating pink eyes and lighter coat colors.

  • Recessive: P = normal, p = mutation. Homozygous pp expresses pink eyes and coat color change.
  • Genotypes:
 * Basic orange Lutino: A_B_C_D_eepp  
 * Cream Lutino (“Shadow”): A_B_C_D_E_pp  

The Lutino gene functions similarly to the non-extension gene but with pink eyes and less effect on pheomelanin. It has been studied extensively in mice (Castle 1909) and rabbits (SoftPawsRabbits, 1985–2014).

References: 1. Rosemblat et al., 1994, PNAS 91:12071–12075 2. Russell, Genetics 34:146, 1949 3. Castle, Science 30(766):313–314, 1909 [SoftPawsRabbits Lutino Gene](https://softpawsrabbits.weebly.com/the-lutino-gene.html)

Modifiers[edit | edit source]

Modifiers are not genes themselves but affect the extent of coverage or intensity of rabbit coat colors.

Intensity of Red[edit | edit source]

Intensity
  • Intensity of red (“Rufus”) controls pheomelanin saturation.
  • Low intensity → almost dirty white
  • High intensity → deep mahogany/maroon
  • Rufus also affects pigment saturation in other colors (e.g., rich black vs. dull charcoal)

Extent of Broken Pattern[edit | edit source]

Extent of Coverage
  • Charlie
  • Broken
  • Blanket
  • Booted

Co-dominant, Cryptic, and Ghost Presentations[edit | edit source]

Some genes present partially dominant traits, show stronger expression when homozygous, or produce “phantom” colors.

ej – Harlequin[edit | edit source]

Harlequin Opal
Harlequin Chinchilla
  • Harlequin (ej) can appear in:
 * Self: aa, Eej  
 * Chinchilla: A, chd, Eej  
 * Chestnut: A, Eej  
  • Ej paired with Steel (Es) can produce “phantom black” or super steel: subtle barring visible only in sunlight or on the belly.

chl – Chinchilla Light / Shaded[edit | edit source]

  • chlchl → Seal (intense shaded pattern)
  • chdchl → Intermediate shaded pattern

Es – Steel[edit | edit source]

  • Genotypes: EsEs, Ese, Esej
  • Can present as solid black in some cases

Ed – Dominant Black[edit | edit source]

  • Extends eumelanin fully on Agouti rabbits (ABCDEd) → appears self black
  • Can produce cryptic self rabbits
  • Testing: breed suspected Ed rabbits with self-colored rabbits or red rabbits to confirm genotype

References: