Difference between revisions of "Baytril"
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Pregnancy category: AU: B3 | *Pregnancy category: AU: B3 | ||
Metabolism: Kidney and non-kidney | *Metabolism: Kidney and non-kidney | ||
Excretion: Bile duct (70%); kidney (30%) | *Excretion: Bile duct (70%); kidney (30%) | ||
AHFS/Drugs.com: International Drug Names | *AHFS/Drugs.com: International Drug Names | ||
ATCvet code: QJ01MA90 (WHO) QD06BA51 (WHO) | *ATCvet code: QJ01MA90 (WHO) QD06BA51 (WHO) | ||
Bioavailability: 80% in dogs, 65-75% in sheep | *Bioavailability: 80% in dogs, 65-75% in sheep | ||
Elimination half-life: 4–5 hours in dogs, 6 hours in cats, 1.5 - 4.5 hours in sheep | *Elimination half-life: 4–5 hours in dogs, 6 hours in cats, 1.5 - 4.5 hours in sheep | ||
*Antimicrobial Agents Used in Rabbits | |||
Revision as of 21:35, 2 August 2023
This antibiotic is widely used in veterinary medicine as an antibacterial agent, showing high activity against both Gram-negative and Gram-positive bacteria Enrofloxacin, sold under the brand name Baytril, among others, is a fluoroquinolone antibiotic used for the treatment of animals. It is a bactericidal agent. The bactericidal activity of enrofloxacin is concentration-dependent, with susceptible bacteria cell death occurring within 20–30 minutes of exposure.
- Pregnancy category: AU: B3
- Metabolism: Kidney and non-kidney
- Excretion: Bile duct (70%); kidney (30%)
- AHFS/Drugs.com: International Drug Names
- ATCvet code: QJ01MA90 (WHO) QD06BA51 (WHO)
- Bioavailability: 80% in dogs, 65-75% in sheep
- Elimination half-life: 4–5 hours in dogs, 6 hours in cats, 1.5 - 4.5 hours in sheep
- Antimicrobial Agents Used in Rabbits
Enrofloxacin uses and doses in Rabbits
Pasteurella Protocol
as been use for Pasteurella and respiratory issues, it more frequently masks of Pasteurella symptoms then cures. Baytril is a Broad spectrum Antibiotic so can be used to treat a wide range of issues, it is stronger then LA 200. Broome RL, Brooks DL. Efficacy of enrofloxacin in the treatment of respiratory pasteurellosis in rabbits. Lab Anim Sci 1991;41:572-576.
GI stasis protocol
• Use only when indicated; enrofloxacin or trimethoprim/sulfa are generally the drugs of choice; use parenterally until stools are passed; metronidazole may be indicated for anaerobe overgrowth
- Broome RL, Brooks DL, Babish JG, et al. Pharmacokinetic properties of enrofloxacin in rabbits. Am J Vet Res 1991;52:1835-1841.
- Cabanes A, Arboix M, Anton JMG, et al. Pharmacokinetics of enrofloxacin after intravenous and intramuscular injection in rabbits. Am J Vet Res 1992;53:2090-2093.
- Elmas M, Uney K, Yazar E, et al. Pharmacokinetics of enrofloxacin following intravenous and intramuscular administration in Angora rabbits. Res Vet Sci 2007;82:242-245.
Drug class:
Dose:
Enrofloxacinb (Baytril, Bayer)
Dosage:
200 mg/L drinking water 14 days
5 mg/kg IM, IV q12-24h44 Angora rabbits/PD
5 mg/kg PO, SC, IM, IV PD;19,23 clinical trial for pasteurellosis, 14 days
5-10 mg/kg PO, SC, IM q12h Pasteurellosis
5-20 mg/kg PO, IM q12h 3 14-30 days Pasteurellosis
Indications:
Side Effects
During Pregnancy or Nursing
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Patient Tips
Drug Interactions
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notes
May cause arthropathies in young dogs, but similar effects using standard dosages in rabbits have not been reported; SC and IM injections may cause muscle necrosis or sterile abscesses; dilute before giving parenterally
