Baytril

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This antibiotic is widely used in veterinary medicine as an antibacterial agent, showing high activity against both Gram-negative and Gram-positive bacteria Enrofloxacin, sold under the brand name Baytril, among others, is a fluoroquinolone antibiotic used for the treatment of animals. It is a bactericidal agent. The bactericidal activity of enrofloxacin is concentration-dependent, with susceptible bacteria cell death occurring within 20–30 minutes of exposure.


Pregnancy category: AU: B3 Metabolism: Kidney and non-kidney Excretion: Bile duct (70%); kidney (30%) AHFS/Drugs.com: International Drug Names ATCvet code: QJ01MA90 (WHO) QD06BA51 (WHO) Bioavailability: 80% in dogs, 65-75% in sheep Elimination half-life: 4–5 hours in dogs, 6 hours in cats, 1.5 - 4.5 hours in sheep



Enrofloxacin uses and doses in Rabbits

Pasteurella Protocol

as been use for Pasteurella and respiratory issues, it more frequently masks of Pasteurella symptoms then cures. Baytril is a Broad spectrum Antibiotic so can be used to treat a wide range of issues, it is stronger then LA 200. Broome RL, Brooks DL. Efficacy of enrofloxacin in the treatment of respiratory pasteurellosis in rabbits. Lab Anim Sci 1991;41:572-576.


GI stasis protocol

• Use only when indicated; enrofloxacin or trimethoprim/sulfa are generally the drugs of choice; use parenterally until stools are passed; metronidazole may be indicated for anaerobe overgrowth





  • Broome RL, Brooks DL, Babish JG, et al. Pharmacokinetic properties of enrofloxacin in rabbits. Am J Vet Res 1991;52:1835-1841.
  • Cabanes A, Arboix M, Anton JMG, et al. Pharmacokinetics of enrofloxacin after intravenous and intramuscular injection in rabbits. Am J Vet Res 1992;53:2090-2093.
  • Elmas M, Uney K, Yazar E, et al. Pharmacokinetics of enrofloxacin following intravenous and intramuscular administration in Angora rabbits. Res Vet Sci 2007;82:242-245.

Drug class:

Dose:

Enrofloxacinb (Baytril, Bayer)

Dosage:

200 mg/L drinking water 14 days

5 mg/kg IM, IV q12-24h44 Angora rabbits/PD

5 mg/kg PO, SC, IM, IV PD;19,23 clinical trial for pasteurellosis, 14 days

5-10 mg/kg PO, SC, IM q12h Pasteurellosis

5-20 mg/kg PO, IM q12h 3 14-30 days Pasteurellosis

Indications:

Side Effects

During Pregnancy or Nursing

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notes

May cause arthropathies in young dogs, but similar effects using standard dosages in rabbits have not been reported; SC and IM injections may cause muscle necrosis or sterile abscesses; dilute before giving parenterally