Editing Draxxin

Their is Officially no known on label  treatment for Pasteurella.

Off label :

Draxin appears to be the most effective treatment and possible a cure when Pasteurella is caught early. Draxin given at the first sign of sneezing and white snot. appears to be effective in  eliminating Pasteurella with in a 72 hour period. More trials are needed. Draxin was used in a piolet study  to test it's effectiveness in rabbits in 2017. 

https://www.semanticscholar.org/paper/Efficacy-of-Tulathramycin-in-the-Treatment-of-in-Edrees-Abdellatief/be26b70bdee671eb3a4b0723e1a4a32409aef421?fbclid=IwAR214Q2aWv2GDy5WlLY4WWJjDIO4Sk8cLXY1UTSEEfdY2vp2dYxzle8u16A
 DOI:10.17582/JOURNAL.AAVS/2017/5.12.477.485Corpus ID: 80507273
 Efficacy of Tulathramycin in the Treatment of Respiratory Pasteurollosis in Rabbits
 N. Edrees, Suhair A. Abdellatief, +1 author Amany El-Sharkawy
 Published 1 November 2017 Medicine, Biology Advances in Animal and Veterinary Sciences
 | Pasteurella multocida is the most critical respiratory bacterial infection of rabbits, around the globe. Beside passive immunization, anti-bacterial treatment is the primary choice of disease control. Since tulathromycin may be retained 
 in the lung for many days after single administration, it can be applied for treatment of respiratory diseases. Hence, the purpose of current study was to evaluate the efficacy of tulathromycin in treating experimentally infected rabbits 
 with P. multocida. In the sensitivity test, tulathromycin showed a potent inhibitory effect on P. multocida compared to several well-established antimicrobial agents. In vivo, treatment with tulathromycin improved clinical signs, mortality 
 rate, lesion scores and growth performance parameters in infected rabbits. Furthermore, treatment with tulathromycin ameliorated the hematological picture, lowered the level of biochemical parameters which were significantly increased due 
 to infection as liver enzymes, blood urea, creatinine and creatine kinase (CK-MB) and elevated the levels of total protein and albumin. Biochemical findings were supported by histopathological picture. It can be concluded that tulathromycin  is an ideal and safe antibiotic for treating infection with Pasteurella multocida in rabbits



We recently interviewed a veterinary zoologist and he and Dr Carpenter ( the author of the exotics formulary that all exotic vet use, have been trying to get Draxxin to be approved for on label treatment of Pasteurella  as a black label drug . FDA is balking currently because rabbits are meat animals and the dry off time is min 60 days , with 120 days till butcher being recommended, as a black label drug    it can only be used in pet stock and stock not intended for consumption.  

Its not that it doesn't work its setting protocol FDA has been balking at 

We did a barn trial on select cull rabbits to test it's effectiveness outside of a laboratory setting, and it had an approx 95%  effective rate as a single dose on a  7 day trial. Rabbits that showed mild symptoms were given a follow up dose 7 days latter and all but 1 has full cleared.  we would like to pursue a grant and  full study to test this further in hope of getting Draxxin approved for  on lable use.
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	We did a barn trial on select cull rabbits to test it's effectiveness outside of a laboratory setting, and it had an approx 95% effective rate as a single dose on a 7 day trial. Rabbits that showed mild symptoms were given a follow up dose 7 days latter and all but 1 has full cleared. we would like to pursue a grant and full study to test this further in hope of getting Draxxin approved for on lable use.		We did a barn trial on select cull rabbits to test it's effectiveness outside of a laboratory setting, and it had an approx 95% effective rate as a single dose on a 7 day trial. Rabbits that showed mild symptoms were given a follow up dose 7 days latter and all but 1 has full cleared. we would like to pursue a grant and full study to test this further in hope of getting Draxxin approved for on lable use.




	~~http://www.veterinaryworld.org/Vol.5/July%202012/Pharmacokinetics%20and%20bioavailability%20of%20tulathromycin%20following%20IV,%20IM%20and%20SC%20administrations%20in%20healthy%20rabbits.pdf~~