Mutations
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Genetic Mutations & Oddities[edit | edit source]
Hermaphroditism and Autofertility[edit | edit source]
- **Frankenhuis et al., 1990** – "A case of combined hermaphroditism and autofertilisation in a domestic rabbit."
* Vet Rec. * [PubMed link](https://pubmed.ncbi.nlm.nih.gov/2382355/)
- **Sheppard, 1943** – "The reproductive system of a pregnant hermaphrodite rabbit (Oryctolagus cuniculus)."
* J Anat. 77(Pt 4): 288–293 * [PMC link](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1252732/)
- **Bayraktar, 2017** – "Potential autofertility in true hermaphrodites."
* Journal of Maternal-Fetal & Neonatal Medicine 31(4):1–10 * DOI:10.1080/14767058.2017.1291619 * [ResearchGate link](https://www.researchgate.net/publication/313454996_Potential_autofertility_in_true_hermaphrodites)
Broken Pattern Oddities[edit | edit source]
- Occasionally, a rabbit may present with a single random white spot (e.g., on the foot). While injury is a likely cause in many cases, the broken gene can sometimes be expressed so subtly that only one hair appears white.
- Key points about Broken patterns:
* Broken is **not** a white rabbit with black patches; it is a **solid-colored rabbit with a white overlay**. * White is a stripping effect caused by genes that block or dilute the density of eumelanin and pheomelanin. * To confirm a rabbit is genetically broken, **test breeding** is required.
- Genes and combinations that can produce broken patterns, random spotting, or “leakage”:
* `En` – Broken * `aachdchd` – Self homozygous Chinchilla * `v` – Vienna * `duw, dud` – Dutch variants * Chimera / somatic gene mutation – genes copied incorrectly during cell division
- [PMC article on gene mutations affecting pigmentation](https://pmc.ncbi.nlm.nih.gov/articles/PMC3695642/)