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=Rabbit Social =
=Rabbit Social =
== 2018 Changes in brain architecture are consistent with altered fear processing in domestic rabbits==
Irene Brusini, Miguel Carneiro, Chunliang Wang, +11, and Leif Andersson https://orcid.org/0000-0002-4085-6968 leif.andersson@imbim.uu.seAuthors Info & Affiliations
Contributed by Leif Andersson, April 21, 2018 (sent for review January 18, 2018; reviewed by Kenneth Hugdahl, and Marcelo R. Sánchez-Villagra)
June 25, 2018  115 (28) 7380-7385  https://doi.org/10.1073/pnas.1801024115
DOMESTICATED  rabbits lost critical thinking skills. Domestic Rabbits Have Reduced Amygdala Size and Increased Medial Prefrontal Cortex Volume.
https://www.pnas.org/doi/10.1073/pnas.1801024115
Abstract
The most characteristic feature of domestic animals is their change in behavior associated with selection for tameness. Here we show, using high-resolution brain magnetic resonance imaging in wild and domestic rabbits, that domestication reduced amygdala volume and enlarged medial prefrontal cortex volume, supporting that areas driving fear have lost volume while areas modulating negative affect have gained volume during domestication. In contrast to the localized gray matter alterations, white matter anisotropy was reduced in the corona radiata, corpus callosum, and the subcortical white matter. This suggests a compromised white matter structural integrity in projection and association fibers affecting both afferent and efferent neural flow, consistent with reduced neural processing. We propose that compared with their wild ancestors, domestic rabbits are less fearful and have an attenuated flight response because of these changes in brain architecture.




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